A-Z OF SKINCARE
F FOR FIBROBLASTS- FIGHT AGEING
Collagen is the protein responsible for the structure, elasticity, and firmness of the skin and it is produced by cells called fibroblasts . The skin undergoes constant changes, with a high capacity of repair and renovation. It is constituted of three main layers: epidermis, dermis, and hypodermis. The epidermis is the outermost layer of the skin. It stands out in the barrier function,
Physiologically, aging is associated with loss of fibrous tissue, slower rate of cell turnover, and reduction of the vascular and glandular network. In addition, the barrier function that maintains cellular hydration is also impaired. Depending on genetics and environmental factors, the normal physiological functions of the skin may decrease by 50% until midlife.The dermis is the layer of skin that possesses the widest variety of cell types such as nerves, blood vessels, and lymph, surrounded by connective tissue formed by fibroblasts, collagen, and reticular and elastic fibers.
During the aging process, the proliferative and metabolic activity of fibroblasts decreases and their functions are impaired, leading to reduction of the synthesis of structural substances such as collagen, elastin, hyaluronic acid, and chondroitin. In addition, decreased levels of growth factors, reduced amount of collagen, abnormal accumulation of elastin, and reduction in the epidermal and dermal thickness, which manifest clinically as xerosis, wrinkles, sagging, blemishes, tonus loss, and all signs of skin aging, were observed during the aging process [24, 25]. Thus, fibroblasts have an important role in preventing the formation of signs of skin aging due to the production of these basic structural substances. Collagen and elastin fibers provide, respectively, firmness and elasticity to the skin. Additionally, mucopolysaccharides, hyaluronic acid, and chondroitin provide skin hydration
WHAT IS THE EVIDENCE?
Studies found that topical application of growth factors ( remember fibroblasts make collagen) resulted in improved photoageing related to the formation of new collagen, epidermal thickening, and improved clinical appearance of the skin with visible reduction of wrinkles.
ZO FIRMING SERUM
An anti-aging breakthrough in skin structure + shape. This mild, lightweight and tolerable formulation is indicated for all skin types and sensitive skin areas to reinforce skin health and hydrate to support the visible improvement in skin elasticity and firmness.
- Visibly tightens and firms the skin
- Improves the appearance of sagging and skin laxity
- Helps define facial contours
- Supports healthy skin structure and the skin’s natural renewal process
- Defends against free radical damage
AVAILABLE UNTIL MAY 31ST 2020.
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